ProArgi 9

Sweeteners in ProArgi-9 Plus

ProArgi 9
ProArgi-9 Plus is Synergy’s top selling nutritional product. One serving contains 5,000 mg (5 grams) of elemental pharmaceutical grade l-arginine. Often referred to as the “miracle molecule,” l-arginine has potent health-enhancing properties.


ProArgi-9 Plus is sweetened naturally with xylitol. Xylitol is natural. Xylitol is a natural occurring carbohydrate. It is found in almost all plant material, including fruits such as raspberries, strawberries, and plums; vegetables; corn husks; and mushrooms. Xylitol is naturally occurring and is nutritive. Xylitol is also naturally produced in the body during normal metabolism. It is produced during metabolism of glucose in the liver. Xylitol is classified as a sugar alcohol, also called a polyol. Polyols are types of carbohydrates. Xylitol is considered a “nutritive sweetener”. It is a low-digestible carbohydrate and is absorbed slowly and incompletely, having a smaller effect on blood glucose. Xylitol provides 2.4 calories per gram and has a glycemic index of 7.

The primary sweetener in ProArgi-9 Plus is xylitol; only a small amount of sucralose is used. There are 35 milligrams of sucralose per 10 gram serving (some markets have a smaller serving size. A 3.25 g serving size contains 13 milligrams of sucralose).

Obstacles in formulating a quality l-arginine product include: 1) arginine itself has a very disagreeable taste. In order to make an arginine supplement palatable, sweeteners (and generally in larger amounts) must be used, and 2) to promote full bioavailability of l-arginine, it is recommended to avoid high glycemic sweeteners, thus most natural sugars cannot be used.

Xylitol is low-glycemic so is a wonderful sweetener option, but it is difficult to formulate with xylitol alone. If we were to remove the 35 milligrams of sucralose, we would need to replace it with several grams of xylitol. This would make the scoop size so large it would be unmanageable. Additionally, consuming large amounts of xylitol may contribute to intestinal symptoms like diarrhea and flatulence.

While there are numerous Internet articles questioning the safety of sucralose, professional and scientific organizations have urged consumers not to believe the Internet conspiracy theories that it is toxic. Sucralose has a very good safety profile and is a superior alternative to potentially harmful artificial sweeteners. The Center for Science in the Public Interest has stated that sucralose is the only artificial sweetener that is considered safe for use without any cautions. This organization cautions against all other artificial sweeteners. They even give sucralose a higher safety rating than natural sugars and sweeteners (
Sucralose is safe to use. While many consumers may still have concerns and choose not to use sucralose in large amounts as their daily sweetener, in cooking, etc., they should have full confidence in consuming ProArgi-9 Plus because of the very small amount of sucralose used and because of the necessity to avoid high glycemic and bulky sweeteners. Again, sucralose is a very safe and desirable sweetener with a very good safety profile.