The meta-analysis, published in Diabetologia, included 64 studies with 858,507 subjects and 28,203 heart attacks and other coronary events.
The studies adjusted for various other cardiovascular risk factors, including age, blood pressure, cholesterol, smoking and body mass index. But when considering diabetes as an independent risk, they found that compared with diabetic men, diabetic women were at a 44 percent higher risk for both fatal and nonfatal cardiovascular events.
The reasons remain unclear, but the study’s lead author, Sanne A. E. Peters, an epidemiologist at University Medical Center Utrecht, suggested that the finding was not because of differences in treatment or physiological differences between the sexes in the effects of diabetes. Rather, it may be a result of the more severe deterioration of women before the onset of diabetes.